Etude phytochimique et activité biologique d'extrait de des feuilles de Phoenix dactylifera L dans la région du Sud d'Algérie (la région d'Oued Souf)

LAOUINI, Salah Eddine (2014) Etude phytochimique et activité biologique d'extrait de des feuilles de Phoenix dactylifera L dans la région du Sud d'Algérie (la région d'Oued Souf). ["eprint_fieldopt_thesis_type_phd" not defined] thesis, Faculté des sciences et de la technologie UMKBiskra.

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Abstract

The date palm (Phoenyx dactylifera L) consisted, for the people of southern Algeria, as tree of providence. Dates and their extracts are also used for many centuries as a medicine against allergy, inflammation, constipation and gastro protective; they also have a high antibacterial and antioxidant activity. However, no studies are conducted to evaluate the extract from the leaves of date palm (Phoenyx dactylifera L) in point of view pharmacology effect. In this study we have evaluated the phytochemical composition, antioxidant antibacterial, antifungal and antimutagenic properties and anti-inflammatory properties determined by measuring the inhibition of nitric oxide (NO) production of leaves extract of three varieties Ghars, Deglet Nour and Hamraya from Phoenyx dactlylifera L. Moreover, the antidiabetic effect was evaluated by inhibition of α-amylase and α-glucosidase enzymes. According to the results, the extracts have very important values for polyphenols, flavanoids, flavonols, condensed tannin, anthocyanin and high antioxidant activity against DPPH, FRAP, ABTS, OH·. Also the three extracts reveal a considerable antimicrobial potency and antifungal considerable activity. The three varieties exhibited significant anti-inflammatory effects using in-vitro inhibition of NO, exhibited potent antimutagenic high inhibitory level of the Ames response induced by the indirect mutagen 2- aminoanthracene and also displayed high inhibition actions against α- amylase and α-glucosidase enzymes. The results suggest that the leaves of the three selected varieties of Phoenyx dactylifera L can be considered as a good source of natural antioxidant, antimicrobial and anti-inflammation drugs as well as potent antidiabetic medicine. Keywords: Phoenyx dactylifera L, leaves, Polyphenols, DPPH, Antidiabetic, Antiinflammatory, antimicrobial, south Algeria.

Item Type: Thesis (["eprint_fieldopt_thesis_type_phd" not defined])
Subjects: T Technology > T Technology (General)
Divisions: Faculté des Sciences et de la technologie > Département de Chimie Industrielle
Depositing User: admin-bu TMLBiskra
Date Deposited: 15 Dec 2015 10:26
Last Modified: 15 Dec 2015 10:26
URI: http://thesis.univ-biskra.dz/id/eprint/1645

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